Santee, South Carolina

South Carolina Orangeburg County Santee Santee is located on the west bank of Lake Marion in Orangeburg County. Ideally situated as a shipping port on the water, this was always a commerce and agricultural center. Today, water sports, fishing, and lake-side living make Santee a popular resort and retirement location.

Orangeburg is the largest city near Santee. Here is a map of the Orangeburg area.

Santee Hotels - a helpful guide - make reservations online

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