SC Charities – Statewide Nonprofit Organizations

South Carolina SC Organizations SC Charities SC Statewide Charities

FEATURED Statewide Nonprofit Organizations

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Choose by Type – SC Charities & Nonprofits

Many South Carolina charities are listed on separate pages according to type. If you do not see the type of non-profit you are looking for in the list below, please look in the next section, called Choose by Name.

Choose by Name – SC Charities & Nonprofits

The list below shows South Carolina charities that are not listed on separate pages under the "Choose by Type" section above. SCIWAY strives to link to every non-profit website in South Carolina. If you would like to add a charity to SCIWAY, please use the form below. And don't forget to check out our entire list of organizations in South Carolina – the organization(s) you're seeking may be listed on a different page.









  • Karuna Prison Yoga - Lexington-based - brings yoga and mindfulness practices to inmates in SC prisons


  • Lions District 32-C - volunteer group participating in community service projects - includes Chesterfield, Clarendon, Darlington, Dillon, Florence, Georgetown, Horry, Kershaw, Lancaster, Lee, Marion, Marlboro, Sumter, and Williamsburg counties


  • Make-A-Wish South Carolina - grants wishes to children with life-threatening medical conditions
  • Midlands Area Consortium for the Homeless - collaborative effort of 60 agencies serving 14 counties
  • Mothers Against Drunk Driving of South Carolina - Columbia-based
    The mission of Mothers Against Drunk Driving is to end drunk driving, help fight drugged driving, support the victims of these violent crimes and prevent underage drinking.
  • Multiple Sclerosis Society - Greater Carolinas Chapter - offers education, support, advocacy and services for people affected by MS
  • Multiplying Good - with a mission to help individuals realize their ability to bring meaningful change to their world, Multiplying Good is delivering impact across SC through immersive training, activation opportunities, and direct ties to a national awards platform, to help people grow as leaders, and producing ripples of good


  • National Federation of the Blind of South Carolina - Columbia-based - works to improve the quality of life for all blind people in South Carolina
  • National Kidney Foundation of South Carolina - Columbia-based - works to increase awareness, prevention and treatment of kidney disease
  • National Youth Advocate Program - North Charleston-based - partners with various governmental and private agencies throughout the state all working together to improve the lives of children and families
  • New Morning Foundation - Columbia-based - works to improve sexual health and family planning
  • No Kill South Carolina - grassroots animal care initiative working with six animal shelters which serve as "Key Resource Centers" to coach, inspire and train vulnerable animal sheltering organizations throughout the state on lifesaving strategies by reducing both the overpopulation and the unnecessary euthanasia





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