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Lake City, SC Hotels & Motels | HotelGuides.com
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Hotels > US Hotels > Hotels in South Carolina > Lake City Hotels & Motels

Hotels and Motels in or near Lake City, SC



Note:  Florence hotels you'll see listed are up to 8 miles farther away than the distance shown.

 
  • Days Inn Lake City
    170 South Ron McNair Blvd, Lake City, SC 29560 Call Us

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    Dates
    Days Inn Lake City

    Check In1400
    Check Out1100

    Rated Average
    • Cheap, smoke-free motel near US 52 at US 378
    • 2 floors, 30 rooms - no elevator
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free continental breakfast
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 275 reviews 
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  • Quality Inn & Suites Lake City
    202 North Ron McNair Blvd, Lake City, SC 29560 Call Us

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    Dates
    Quality Inn & Suites Lake City

    Check In15 00
    Check Out11 00

    Rated High
    • Midscale, smoke-free motel in downtown Lake City
    • 2 floors, 56 rooms and suites - no elevator
    • No swimming pool
    • Exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 9 reviews 
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  • Inn at the Crossroads Lake City
    128 West Main Street, Lake City, SC 29560 Call Us

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    Dates
    Inn at the Crossroads Lake City

    Check In15 00
    Check Out11 00

    • Upscale, smoke-free, full-service, downtown hotel
    • Near Moore Farms Botanical Garden
    • 3 floors, 57 rooms and suites - elevator
    • No swimming pool
    • Exercise room
    • Restaurant - lounge
    • Restaurant open for dinner only
    • Free WiFi
    • Free parking
    • Not pet friendly

  • Travelodge Florence - I-95, Exit 157
    3783A West Palmetto Street, I-95, Exit 157, Florence, SC 29502 Call Us 21 miles
    21 miles from Lake City

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    Dates
    Travelodge Florence - I-95, Exit 157

    Check In14 00
    Check Out11 00

    Rated Very Low – Not Recommended
    • Cheap, interstate motel near I-95 at US 76
    • 2 floors, 50 rooms - no elevator
    • Some smoking rooms
    • Outdoor swimming pool open in summer
    • Microwave and refrigerator in every room
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  2.5 of 5 stars
    Based on 278 reviews 
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  • Affordable Suites of America Florence - I-95, Exit 160
    530 Woody Jones Blvd, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Affordable Suites of America Florence - I-95, Exit 160

    Check In1500
    Check Out1100

    Rated Very High
    • Budget, smoke-free, all-suite, extended-stay motel
    • Near Florence Center
    • 2 floors, 29 suites - no elevator
    • No swimming pool
    • Kitchen in every suite
    • Free WiFi
    • Free parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 41 reviews 
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  • Comfort Inn & Suites Florence - I-95, Exit 160
    527 Woody Jones Blvd, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Comfort Inn & Suites Florence - I-95, Exit 160

    Check In16 00
    Check Out11 00

    Rated High
    • Midscale, smoke-free hotel near Florence Center
    • Also near I-20 Business, Exit 141
    • 3 floors, 89 rooms and suites - elevator
    • Outdoor swimming pool open in summer Exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - limited truck parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 77 reviews 
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  • Home2 Suites by Hilton Florence - I-95, Exit 160
    900 Woody Jones Blvd, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Home2 Suites by Hilton Florence - I-95, Exit 160

    Check In15 00
    Check Out11 00

    Rated Average
    • Upper-midscale, smoke-free, extended-stay hotel
    • Near Florence Center
    • 5 floors, 83 studio and 1-bedroom suites
    • Indoor swimming pool - exercise room
    • Kitchen in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 862 reviews 
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  • Fairfield Inn & Suites by Marriott Florence - I-95, Exit 160
    501 Woody Jones Blvd, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Fairfield Inn & Suites by Marriott Florence - I-95, Exit 160

    Check In1600
    Check Out1100

    Rated High
    • Upper-midscale, smoke-free hotel
    • Near Florence Center
    • 4 floors, 70 rooms, 16 suites
    • Heated indoor swimming pool
    • 24-hour exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 206 reviews 
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  • Residence Inn by Marriott Florence - I-95, Exit 160
    2660 Hospitality Blvd, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Residence Inn by Marriott Florence - I-95, Exit 160

    Check In1600
    Check Out1100

    Rated High
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • Near Florence Center
    • 4 floors, 94 suites
    • Outdoor swimming pool open all year
    • 24-hour exercise room
    • Kitchen in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 527 reviews 
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  • SpringHill Suites by Marriott Florence - I-95, Exit 160
    2670 Hospitality Blvd, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    SpringHill Suites by Marriott Florence - I-95, Exit 160

    Check In1600
    Check Out1100

    Rated Very High
    • Upscale, smoke-free, all-suite hotel near I-95
    • Also near Florence Civic Center
    • 4 floors, 95 suites
    • Heated indoor swimming pool - exercise room
    • Microwave and refrigerator in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking - truck parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 649 reviews 
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  • Courtyard by Marriott Florence - I-95, Exit 160
    2680 Hospitality Blvd, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Courtyard by Marriott Florence - I-95, Exit 160

    Check In1600
    Check Out1100

    Rated High
    • Upscale, smoke-free hotel
    • Near Florence Center
    • 3 floors, 90 rooms and suites - elevator
    • Indoor swimming pool - exercise room
    • Restaurant - lounge
    • Restaurant open for breakfast and dinner only
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 560 reviews 
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  • TownePlace Suites by Marriott Florence - I-95, Exit 160
    2650 Hospitality Blvd, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    TownePlace Suites by Marriott Florence - I-95, Exit 160

    Check In1600
    Check Out1100

    Rated Very High
    • Midscale, smoke-free, all-suite, extended-stay hotel
    • Near Florence Center and I-95 at I-20
    • 4 floors, 89 suites
    • Outdoor swimming pool - exercise room
    • Kitchen in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 257 reviews 
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  • Staybridge Suites Civic Center Florence - I-95, Exit 160
    150 Westpark Drive, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Staybridge Suites Civic Center Florence - I-95, Exit 160

    Check In16 00
    Check Out12 00

    Rated Very High
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • Near Florence Center
    • 8 floors, 112 studio to 2-bedroom suites
    • Outdoor swimming pool - 24-hour exercise room
    • Kitchen in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  5.0 of 5 stars
    Based on 139 reviews 
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  • Hilton Garden Inn Florence - I-95, Exit 160
    2671 Hospitality Blvd, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Hilton Garden Inn Florence - I-95, Exit 160

    Check In15 00
    Check Out12 00

    Rated Average
    • Upscale, smoke-free hotel near I-95
    • Also near Florence Center
    • 8 floors, 186 rooms and suites
    • Heated indoor swimming pool - exercise room
    • Restaurant - lounge - room service
    • Restaurant open for breakfast and dinner only
    • Microwave and refrigerator in every room
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 1082 reviews 
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    More Reviews

  • Holiday Inn Express & Suites Civic Center Florence - I-95, Exit 160
    3440 West Radio Drive, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Holiday Inn Express & Suites Civic Center Florence - I-95, Exit 160

    Check In16 00
    Check Out11 00

    Rated Very High
    • Upper-midscale, smoke-free hotel near I-95 at I-20
    • Also near Florence Center
    • 3 floors, 87 rooms and suites - elevator
    • Heated indoor swimming pool - exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 533 reviews 
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  • Homewood Suites by Hilton Civic Center Florence - I-95, Exit 160
    3450 West Radio Drive, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Homewood Suites by Hilton Civic Center Florence - I-95, Exit 160

    Check In15 00
    Check Out12 00

    Rated High
    • Upscale, smoke-free, all-suite, extended-stay hotel
    • Near I-95 at I-20, Exit 141
    • Also near Florence Center
    • 4 floors, 97 studio to 1-bedroom suites
    • Heated indoor swimming pool - exercise room
    • Kitchen in every suite
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.0 of 5 stars
    Based on 205 reviews 
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  • Hampton Inn & Suites Civic Center Florence - I-95, Exit 160
    3000 West Radio Drive, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Hampton Inn & Suites Civic Center Florence - I-95, Exit 160

    Check In15 00
    Check Out12 00

    Rated High
    • Upper-midscale, smoke-free hotel
    • Near I-95 and civic center
    • Also near GE and Magnolia Mall
    • 3 floors, 82 rooms and suites - elevator
    • Outdoor swimming pool open all year - exercise room
    • Microwave and refrigerator in every room
    • Free hot breakfast buffet
    • Free WiFi
    • Free parking
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 674 reviews 
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  • Hyatt Place Hotel Downtown Florence
    100 East Evans Street, Florence, SC 29506 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Hyatt Place Hotel Downtown Florence

    Check In15 00
    Check Out11 00

    Rated High
    • Upscale, smoke-free, full-service, downtown hotel
    • 5 floors, 106 rooms and suites
    • Outdoor swimming pool open in summer
    • Exercise room
    • Restaurant - lounge
    • Free WiFi
    • Free parking
    • Pet friendly hotel More >
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 188 reviews 
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  • Hotel Florence
    126 West Evans Street, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Hotel Florence

    Check In15 00
    Check Out11 00

    Rated Very High
    • Upscale, smoke-free, full-service, downtown hotel
    • 3 miles from Florence Airport
    • A Tapestry Collection by Hilton hotel
    • 3 floors, 64 rooms - elevator
    • No shuttle to Florence Airport
    • No swimming pool
    • Exercise room
    • Restaurant - lounge - room service
    • Free WiFi
    • Free parking
    • Park and fly not allowed
    • Not pet friendly
  • TripAdvisor Traveler Rating:  4.5 of 5 stars
    Based on 604 reviews 
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  • Red Roof Inn Florence - I-95, Exit 160
    2690 David McLeod Blvd, I-95, Exit 160, Florence, SC 29501 Call Us 22 miles
    22 miles from Lake City

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    Dates
    Red Roof Inn Florence - I-95, Exit 160

    Check In15 00
    Check Out11 00

    Rated Average
    • Cheap, smoke-free motel near I-95
    • Also near Florence Civic Center
    • 2 floors, 112 rooms - no elevator
    • No swimming pool
    • Free WiFi
    • Free parking
    • Pet friendly motel More >
  • TripAdvisor Traveler Rating:  3.5 of 5 stars
    Based on 470 reviews 
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We can also help you find hotels in Lake City, Florida and in Rocky Top, Tennessee, formerly Lake City, Tennessee.

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Lake City Info

Lake City Group Hotel Rates

Hotels near Me

Nearby Attractions


Hotels near Williamsburg Federal Prison   21 miles south
Hotels near Florence National Cemetery   21 miles north
Hotels near Florence Center   22 miles north
Pet Friendly Lake City Hotels near I-95   22 miles north
Hotels near Sexton Dental Clinic   22 miles north
Hotels near McLeod Regional Medical Center   22 miles north
Hotels near Downtown Florence   22 miles north
Hotels near Florence Airport – FLO   22 miles north
Hotels near Magnolia Mall   22 miles north
Hotels near Francis Marion University   23 miles north
Hotels near Highway 52 Florence   25 miles north

Nearby Cities


Kingstree SC Hotels   15 miles south
Turbeville SC Hotels   15 miles west
Hemingway SC Hotels   19 miles SE
Timmonsville SC Hotels   21 miles NW
Florence SC Hotels   22 miles north
Marion SC Hotels   29 miles NE
How Do We Order Hotels?

On place pages like this, we order hotels from lowest cost to highest – except we list low-rated hotels at the bottom of the page.

Most of our competitors order these same hotels in other ways that make them more money.
How Do We Define Motel?

To us, motels are smaller lodgings that have rooms you can enter directly from the parking area.

At hotels, on the other hand, you can enter your room only through a hall inside the building.
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Hotel Booking Tips
  1. Beware of non-refundable reservations that could cost you a lot of money if you change or cancel them. +Non-refundable reservations are a gamble that will usually save you less than $10. If you make a $90 non-refundable reservation instead of a $100 refundable booking, you are betting $90 to win $10. Would you do that in Las Vegas?
  2. Don't assume you can cancel a non-refundable reservation without penalty if you notify the hotel weeks or even months in advance. +Often you cannot – because some hotels' profit strategy is to get paid more than once for the same room for the same night.
  3. Always read cancellation policies carefully before you make a reservation. + When is the latest date and time you can cancel without penalty?
    More >
  4. When you make a reservation, you will receive a confirmation email. Take a copy with you to the hotel.
  5. The earlier in the afternoon you check into a hotel, the more likely you will get a room or suite that matches your preferences.



Lake City Hotels, Motels, Lodging, and Accommodations – Lake City, South Carolina SC, USA

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